Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ACPL_3818Two-component system, NarL family, response regulator DesR; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (203 aa)    
Predicted Functional Partners:
ACPL_3817
Two-component system, NarL family, sensor histidine kinase DesK; Signal transduction histidine kinase.
 
  0.995
ACPL_4298
Two-component system, NarL family, sensor histidine kinase DesK; Signal transduction histidine kinase.
 
  0.980
ACPL_3339
Two-component system, NarL family, sensor histidine kinase DesK; Signal transduction histidine kinase.
 
  0.976
ACPL_3816
ABC-2 type transporter; ABC-type multidrug transport system, permease component.
 
     0.814
ACPL_3815
Spermidine/putrescine import ATP-binding protein potA; ABC-type sugar transport systems, ATPase components.
 
     0.800
ACPL_3814
Platelet-activating factor acetylhydrolase 2, cytoplasmic; Predicted dienelactone hydrolase.
       0.727
ACPL_3850
Nitrate/nitrite sensor protein narQ; Signal transduction histidine kinase.
  
   0.724
ACPL_2515
Two-component system sensor kinase; Signal transduction histidine kinase.
  
   0.712
ACPL_6206
Signal transduction histidine kinase.
  
   0.702
ACPL_4240
Signal transduction histidine kinase.
  
   0.696
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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