Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_38472-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate synthase; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (229 aa)    
Predicted Functional Partners:
sucA
2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
   
 0.686
ACPL_4084
Hypothetical protein.
  
     0.681
macB
Macrolide export ATP-binding/permease protein macB; ABC-type antimicrobial peptide transport system, permease component.
  
     0.636
ACPL_1533
2-oxoisovalerate dehydrogenase E1 component; Transketolase.
   
 0.545
ACPL_3124
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
   
 0.545
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.532
ACPL_3848
Selenocysteine lyase.
       0.515
menC
O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
    
 0.512
ACPL_3122
Bifunctional protein glmU; Acetyltransferase (isoleucine patch superfamily).
 
 
 0.479
ACPL_687
Hypothetical protein.
  
     0.461
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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