Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
rpgRX-linked retinitis pigmentosa GTPase regulator; Alpha-tubulin suppressor and related RCC1 domain-containing proteins. (769 aa)    
Predicted Functional Partners:
ACPL_3859
Hypothetical protein; Transcription-repair coupling factor (superfamily II helicase).
 
     0.801
ACPL_3857
Hypothetical protein.
       0.773
ACPL_3858
Response regulator containing a CheY-like receiver domain and a GGDEF domain.
       0.773
ACPL_3860
Hypothetical protein.
       0.601
ppiB-2
Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family.
  
 
  0.535
st2
Carbonic anhydrase; Sulfate permease and related transporters (MFS superfamily).
   
   0.533
pks3B
Polyketide synthase modules and related proteins.
  
 
   0.529
pks2A
Polyketide synthase modules and related proteins.
    
   0.525
ACPL_457
NADH:ubiquinone oxidoreductase subunit 4 (chain M).
    
 
 0.524
ACPL_746
NADH:ubiquinone oxidoreductase subunit 4 (chain M).
    
 
 0.524
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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