Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_3869Mlc-like protein; Transcriptional regulator/sugar kinase. (385 aa)    
Predicted Functional Partners:
ACPL_3868
Transcriptional regulators.
     
 0.777
ACPL_8032
ROK family protein; Transcriptional regulator/sugar kinase.
  
    0.757
pfkB
Fructokinase; Sugar kinases, ribokinase family.
  
  
 0.694
ACPL_3867
yihS-like uncharacterized sugar isomerase; N-acyl-D-glucosamine 2-epimerase.
       0.688
manB-3
Beta-mannosidase; Beta-galactosidase/beta-glucuronidase.
 
   
 0.597
ACPL_3870
Uncharacterized protein; ABC-type sugar transport system, periplasmic component.
  
  
 0.521
malG
ABC-type sugar transport system, permease component.
     
 0.520
ACPL_3871
ABC-type sugar transport systems, permease components.
       0.517
ACPL_3874
Endo-beta-mannanase.
       0.509
gltB
Glutamate synthase domain 2.
     
 0.444
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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