Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
manB-3Beta-mannosidase; Beta-galactosidase/beta-glucuronidase. (797 aa)    
Predicted Functional Partners:
manB-2
Beta-mannosidase; Beta-galactosidase/beta-glucuronidase.
  
  
 
0.906
ACPL_3870
Uncharacterized protein; ABC-type sugar transport system, periplasmic component.
 
     0.837
ACPL_3874
Endo-beta-mannanase.
 
  
  0.828
ACPL_3871
ABC-type sugar transport systems, permease components.
  
    0.786
malG
ABC-type sugar transport system, permease component.
       0.782
bga-2
Beta-galactosidase.
 
 
 0.754
bga
Beta-galactosidase.
 
 
 0.744
ACPL_3876
ATP-binding cassette, subfamily B, bacterial; ABC-type multidrug transport system, ATPase and permease components.
 
     0.648
ACPL_3869
Mlc-like protein; Transcriptional regulator/sugar kinase.
 
   
 0.597
ACPL_4099
Cellulase; Endoglucanase.
  
 
 0.578
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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