Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_3874Endo-beta-mannanase. (826 aa)    
Predicted Functional Partners:
ACPL_3870
Uncharacterized protein; ABC-type sugar transport system, periplasmic component.
 
     0.888
pfkB
Fructokinase; Sugar kinases, ribokinase family.
    
  0.885
manB-3
Beta-mannosidase; Beta-galactosidase/beta-glucuronidase.
 
  
  0.828
ACPL_3871
ABC-type sugar transport systems, permease components.
 
     0.802
malG
ABC-type sugar transport system, permease component.
 
     0.801
frk2
Fructokinase; Sugar kinases, ribokinase family.
     
  0.800
manA
Glucosylceramidase; Beta-mannanase; Belongs to the glycosyl hydrolase 26 family.
 
     0.720
ACPL_3652
Glutamine amidotransferase, class-II; Beta-mannanase; Belongs to the glycosyl hydrolase 26 family.
 
     0.700
ACPL_4904
Secreted hydrolase; Beta-mannanase; Belongs to the glycosyl hydrolase 26 family.
 
     0.699
ACPL_3879
Beta-mannanase; Belongs to the glycosyl hydrolase 26 family.
 
     0.697
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (16%) [HD]