Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_3917Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (448 aa)    
Predicted Functional Partners:
ACPL_3916
Flavin-containing monooxygenase FMO; Predicted flavoprotein involved in K+ transport.
 
     0.902
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 0.900
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
  
 0.781
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
 0.781
pks2A
Polyketide synthase modules and related proteins.
  
 0.775
pks1B
Polyketide synthase modules and related proteins.
  
 0.769
pks3B
Polyketide synthase modules and related proteins.
  
 0.769
pks3C
Polyketide synthase modules and related proteins.
  
 0.755
ACPL_4252
Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
 
 0.753
ACPL_3915
Carbohydrate diacid regulator; Regulator of polyketide synthase expression.
 
     0.741
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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