STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_4029Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (234 aa)    
Predicted Functional Partners:
nnrD
Hydroxyethylthiazole kinase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
 
    0.881
ACPL_4027
Putative signaling protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
       0.576
ACPL_4030
Uncharacterized protein conserved in bacteria.
       0.547
pgk
3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
     
 0.532
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.521
eno-2
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.521
cobI
Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Precorrin-3B methylase.
  
  
 0.498
ACPL_4031
Uncharacterized protein; Predicted RNA polymerase sigma factor containing a TPR repeat domain; Belongs to the sigma-70 factor family.
       0.461
cobE
Protein cobE; Cobalamin biosynthesis protein CbiG.
  
  
 0.431
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.