STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_4034Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. (141 aa)    
Predicted Functional Partners:
pcaB
3-carboxy-cis,cis-muconate cycloisomerase; Adenylosuccinate lyase.
 
 
 0.951
ACPL_2370
4-carboxymuconolactone decarboxylase; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
  
0.921
ACPL_4035
Heavy metal-dependent transcription regulator 2; Predicted transcriptional regulators.
 
     0.911
ACPL_6319
2-hydroxy-6-oxononadienedioate/2-hydroxy-6- oxononatrienedioate hydrolase 1; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
    
 0.902
ACPL_7946
Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
    
 0.902
ACPL_4033
yesE-like uncharacterized protein; Ketosteroid isomerase-related protein.
       0.780
ACPL_2588
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
 
  
 0.596
ACPL_4042
2-hydroxy-3-oxopropionate reductase; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
 
  
 0.594
pobA
P-hydroxybenzoate 3-monooxygenase; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.
 
   
 0.580
ACPL_4036
Hypothetical protein.
       0.545
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.