Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_40422-hydroxy-3-oxopropionate reductase; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases. (253 aa)    
Predicted Functional Partners:
ACPL_4041
Endoribonuclease L-PSP; Putative translation initiation inhibitor, yjgF family.
       0.780
ACPL_4043
Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
 
   
 0.652
ACPL_2370
4-carboxymuconolactone decarboxylase; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
  
 0.483
ACPL_4044
Amidohydrolase 2; Predicted metal-dependent hydrolase of the TIM-barrel fold.
       0.455
ACPL_4034
Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.
 
  
 0.438
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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