STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_4044Amidohydrolase 2; Predicted metal-dependent hydrolase of the TIM-barrel fold. (295 aa)    
Predicted Functional Partners:
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.692
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.625
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.625
ACPL_4043
Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
       0.536
ACPL_4041
Endoribonuclease L-PSP; Putative translation initiation inhibitor, yjgF family.
  
    0.504
ACPL_4771
Predicted integral membrane protein.
  
     0.500
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
  
  
 0.482
lamA
Biotin carboxylase.
     
 0.458
ACPL_4042
2-hydroxy-3-oxopropionate reductase; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
       0.452
metH
5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
    0.424
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.