Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ACPL_4055Deoxyhypusine hydroxylase; Predicted transcriptional regulators. (331 aa)    
Predicted Functional Partners:
ACPL_4054
Hypothetical protein; FOG: HEAT repeat.
 
     0.950
ACPL_4056
Hypothetical protein.
       0.757
efp
Elongation factor EF-P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
 0.632
phoR
Sensory box histidine kinase PhoR; Signal transduction histidine kinase.
   
 
 0.575
ACPL_3427
Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Osmosensitive K+ channel histidine kinase.
   
 
 0.575
ACPL_4053
Lysophospholipase NTE1; Predicted esterase of the alpha-beta hydrolase superfamily.
       0.564
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
   
 
 0.547
holB
DNA polymerase III subunit delta; ATPase involved in DNA replication.
   
  0.544
ACPL_4809
Two-component system sensor protein; Signal transduction histidine kinase.
   
 
 0.542
dnaZ
DNA polymerase III, gamma/tau subunits.
   
  0.539
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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