STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccdACytochrome c biogenesis protein. (262 aa)    
Predicted Functional Partners:
ccsA
ABC-type transport system involved in cytochrome c biogenesis, permease component.
 
  
 0.995
resB
ResB protein required for cytochrome c biosynthesis.
 
  
 0.994
resA
Alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; Thiol-disulfide isomerase and thioredoxins.
 
  
 0.991
ACPL_405
Phosphoglycerate mutase; Fructose-2,6-bisphosphatase.
  
    0.944
hemL-3
Glutamate-1-semialdehyde aminotransferase.
  
  
 0.942
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
  
 0.747
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
     
 0.727
ctaE
Heme/copper-type cytochrome/quinol oxidase, subunit 3.
  
   
 0.697
hemD
Uroporphyrinogen-III synthase.
  
    0.609
ACPL_8101
Thiol:disulfide interchange protein dsbE; Thiol-disulfide isomerase and thioredoxins.
 
  
 0.604
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.