Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_4079Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (459 aa)    
Predicted Functional Partners:
gabT-2
4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.983
ACPL_7756
NAD-dependent aldehyde dehydrogenases.
 
     0.934
gabT
4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.930
sdhA
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
   
 0.918
sucA
2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
  
 0.918
sdhA-2
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
   
 0.918
sdhB
Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
   
 
 0.905
sdhb
Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
   
 
 0.905
gabD
Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.902
sdhC
Succinate dehydrogenase cytochrome b-556 subunit.
     
  0.900
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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