STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gabT-24-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (446 aa)    
Predicted Functional Partners:
ACPL_4079
Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
 
 0.984
gabD
Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
 
 0.931
msmA
NAD-dependent aldehyde dehydrogenases.
  
 0.930
gadB
Glutamate decarboxylase and related PLP-dependent proteins; Belongs to the group II decarboxylase family.
  
 0.930
ACPL_7671
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
 
 0.930
ACPL_7755
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
 
 0.930
ACPL_2463
4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.921
fadB
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; 3-hydroxyacyl-CoA dehydrogenase.
    
 0.911
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
     
 0.907
panC
Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
     
 0.903
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.