Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
macBMacrolide export ATP-binding/permease protein macB; ABC-type antimicrobial peptide transport system, permease component. (433 aa)    
Predicted Functional Partners:
ACPL_4084
Hypothetical protein.
 
 0.981
ACPL_4085
Lipoprotein-releasing system ATP-binding protein; ABC-type spermidine/putrescine transport systems, ATPase components.
 
 
 0.958
ACPL_2322
Multidrug resistance protein mdtA; Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.741
ACPL_2933
Putative macrolide-specific efflux protein macA; Membrane-fusion protein.
 
 0.733
ttgG
Toluene efflux pump periplasmic linker protein ttgG; Membrane-fusion protein.
 
 0.721
ACPL_3621
Heat repeat-containing PBS lyase; Predicted NTPase (NACHT family).
  
     0.720
ACPL_2323
Membrane-fusion protein.
 
 0.697
cusB
DNA-directed RNA polymerase subunit beta; Membrane-fusion protein.
 
 0.663
ACPL_8359
Hypothetical protein.
  
     0.653
ACPL_3847
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate synthase; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
     0.636
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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