Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ccsAABC-type transport system involved in cytochrome c biogenesis, permease component. (324 aa)    
Predicted Functional Partners:
resB
ResB protein required for cytochrome c biosynthesis.
 
  
 0.995
ccdA
Cytochrome c biogenesis protein.
 
  
 0.991
resA
Alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; Thiol-disulfide isomerase and thioredoxins.
  
  
 0.985
ACPL_405
Phosphoglycerate mutase; Fructose-2,6-bisphosphatase.
  
    0.912
hemD
Uroporphyrinogen-III synthase.
  
  
 0.906
hemL-3
Glutamate-1-semialdehyde aminotransferase.
 
  
 0.903
cydCD
Multidrug resistance protein 2; ABC-type multidrug transport system, ATPase and permease components.
     
  0.783
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.716
cysG
uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Uroporphyrinogen-III methylase.
  
  
 0.705
modB
Putative sulfate transport system permease protein cysT; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
   
 
 0.694
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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