Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ACPL_4096Hypothetical protein. (287 aa)    
Predicted Functional Partners:
ACPL_5140
Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.
  
 0.747
ACPL_4095
Serine phosphatase RsbU, regulator of sigma subunit.
       0.723
ACPL_4097
Urease operon transcriptional activator; Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.
 
     0.700
cheA
Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.
  
 0.573
ACPL_7936
Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.
  
 0.573
phoR
Sensory box histidine kinase PhoR; Signal transduction histidine kinase.
  
 
 0.545
ACPL_3427
Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Osmosensitive K+ channel histidine kinase.
  
 
 0.545
ACPL_6499
Transcriptional activator ligand binding domain protein.
  
     0.543
ACPL_1485
Chemotaxis signal transduction protein.
  
 0.530
ACPL_2203
Chemotaxis signal transduction protein.
  
 0.530
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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