Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiX; 3-polyprenyl-4-hydroxybenzoate decarboxylase. (205 aa)    
Predicted Functional Partners:
ubiD
3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiD; 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family.
 
 
 0.998
ubiA
Prenyltransferase; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; Belongs to the UbiA prenyltransferase family.
 
  
 0.996
ACPL_2972
FMN reductase; Predicted flavoprotein.
     
  0.900
ACPL_4734
5,6-dimethylbenzimidazole biosynthesis protein BluB; Nitroreductase.
     
  0.900
ACPL_6801
FMN-dependent NADH-azoreductase; Predicted flavoprotein.
     
  0.900
mqnE
FO synthase subunit 2 1; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
 
   
 0.820
mqnA
Periplasmic solute-binding protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
   
 0.800
mqnC
Radical SAM domain-containing protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
   
 0.780
mqnD
Periplasmic solute-binding protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
 
     0.746
ACPL_1542
Coenzyme A biosynthesis bifunctional protein coaBC; Phosphopantothenoylcysteine synthetase/decarboxylase.
    
  0.667
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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