Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
degU-2Transcriptional regulatory protein degU; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (199 aa)    
Predicted Functional Partners:
ACPL_6206
Signal transduction histidine kinase.
  
   0.669
ACPL_4137
Transcriptional regulator, LuxR family; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
    
0.667
ACPL_6730
Signal transduction histidine kinase.
 
   0.654
ACPL_4240
Signal transduction histidine kinase.
  
   0.638
ACPL_7237
Signal transduction histidine kinase.
  
   0.630
ACPL_4132
Hypothetical protein.
 
     0.628
ACPL_3850
Nitrate/nitrite sensor protein narQ; Signal transduction histidine kinase.
  
   0.627
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
   
 
 0.626
ACPL_5666
Signal transduction histidine kinase.
  
   0.623
ACPL_2318
Signal transduction histidine kinase.
  
 
 0.622
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.