Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_4137Transcriptional regulator, LuxR family; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (220 aa)    
Predicted Functional Partners:
degU-2
Transcriptional regulatory protein degU; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
    
0.667
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
   
 
 0.626
ACPL_2318
Signal transduction histidine kinase.
  
 
 0.622
ACPL_4139
Putative metalloprotease; Membrane proteins related to metalloendopeptidases.
 
     0.608
ACPL_2274
Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
 
 0.597
ACPL_4138
2',3'-cyclic-nucleotide 2'-phosphodiesterase; Predicted HD superfamily hydrolase.
       0.554
ACPL_4809
Two-component system sensor protein; Signal transduction histidine kinase.
   
 
 0.533
ACPL_4800
Two-component system, cell cycle sensor kinase and response regulator; Signal transduction histidine kinase.
   
 
 0.503
ACPL_1209
Signal transduction histidine kinase.
  
   0.496
ACPL_5272
Sensor protein vraS; Signal transduction histidine kinase.
  
   0.486
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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