STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpcE5-oxopent-3-ene-1,2,5- tricarboxylatedecarboxylas E; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases). (643 aa)    
Predicted Functional Partners:
frk2
Fructokinase; Sugar kinases, ribokinase family.
    
  0.810
pfkB
Fructokinase; Sugar kinases, ribokinase family.
    
  0.810
hmgA
Homogentisate 1,2-dioxygenase.
  
  
 0.687
nrm
Nurim; Putative protein-S-isoprenylcysteine methyltransferase.
       0.682
argH
Argininosuccinate lyase.
 
  
 0.528
manR
Mandelate racemase; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
  
 0.465
putA
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
  
 
 0.444
ACPL_4159
Glycosyl transferase family protein; Membrane carboxypeptidase (penicillin-binding protein).
       0.401
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.