Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_424Vitamin B12-binding protein; ABC-type Fe3+-hydroxamate transport system, periplasmic component. (309 aa)    
Predicted Functional Partners:
ACPL_426
Iron complex transport system ATP-binding protein; ABC-type sugar transport systems, ATPase components.
 
 0.980
ACPL_425
Vitamin B12 import system permease protein btuC; ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 0.979
fepD
Vitamin B12 import system permease protein btuC; ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 0.892
fepC
Iron complex transport system ATP-binding protein; ABC-type oligopeptide transport system, ATPase component.
 
 0.849
fepG
Vitamin B12 import system permease protein btuC; ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.786
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.693
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.693
ACPL_2439
Phosphate import ATP-binding protein pstB; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
    
 0.672
ACPL_6195
Polyketide synthase modules and related proteins.
  
  
 0.672
ACPL_882
Peptide/nickel transport system substrate-binding protein; ABC-type dipeptide transport system, periplasmic component.
     
 0.651
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.