Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ACPL_4240Signal transduction histidine kinase. (317 aa)    
Predicted Functional Partners:
ACPL_4239
Transcriptional regulatory protein degU; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
   0.960
ACPL_6207
Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
   0.832
ACPL_5253
yxjL-like uncharacterized transcriptional regulatory protein; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
   0.819
ACPL_1915
Transcriptional regulatory protein liaR; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
   0.814
ACPL_1954
Transcriptional regulatory protein ydfI; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
   0.811
ACPL_6805
yhcZ-like uncharacterized transcriptional regulatory protein; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
  
   0.811
ACPL_7236
Nitrate/nitrite response regulator protein narP; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
   0.811
ACPL_5146
Transcriptional regulatory protein desR; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
   0.810
ACPL_5273
yfiK-like uncharacterized transcriptional regulatory protein; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
   0.809
ACPL_2513
Transcriptional regulatory protein degU; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
   0.808
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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