Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_4261Uncharacterized protein; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (478 aa)    
Predicted Functional Partners:
ACPL_4649
Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.
  
 
 0.770
ACPL_397
Serine phosphatase RsbU, regulator of sigma subunit.
  
 
 0.721
ACPL_3780
Magnesium or manganese-dependent protein phosphatase; FOG: PAS/PAC domain.
  
 
 0.716
ACPL_381
Phosphoserine phosphatase rsbX; Anti-sigma regulatory factor (Ser/Thr protein kinase).
  
 
 0.701
rsbU-5
Uncharacterized protein; Serine phosphatase RsbU, regulator of sigma subunit.
  
 
 0.674
ACPL_2318
Signal transduction histidine kinase.
  
  
 0.573
ACPL_7226
Multi-sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.
  
 
 0.551
ACPL_2274
Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
  
 0.542
ACPL_379
Acetoacetate metabolism regulatory protein atoC; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
  
   0.541
ACPL_3421
Osmosensitive K+ channel histidine kinase.
  
  
 0.530
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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