ACPL_4294 protein (Actinoplanes sp. SE50110)

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Score

ACPL_4294

Uncharacterized protein; ATPases with chaperone activity, ATP-binding subunit. (232 aa)

Predicted Functional Partners:

clpP-3

0.914

clpP-2

0.741

clpP-4

0.741

clpP

0.727

dnaJ

0.706

dnaJ-2

0.706

clpS

0.703

clpC-2

0.703

grpE

0.685

ACPL_4783

0.676

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACPL_4294	ACPL_4783	ACPL_4294	ACPL_4783	Uncharacterized protein; ATPases with chaperone activity, ATP-binding subunit.	Nephrocystin-3; FOG: TPR repeat.	0.676
ACPL_4294	clpC-2	ACPL_4294	ACPL_6603	Uncharacterized protein; ATPases with chaperone activity, ATP-binding subunit.	clpA-like ATP-dependent Clp protease; ATPases with chaperone activity, ATP-binding subunit.	0.703
ACPL_4294	clpP	ACPL_4294	ACPL_1841	Uncharacterized protein; ATPases with chaperone activity, ATP-binding subunit.	Protease subunit of ATP-dependent Clp proteases; Belongs to the peptidase S14 family.	0.727
ACPL_4294	clpP-2	ACPL_4294	ACPL_1353	Uncharacterized protein; ATPases with chaperone activity, ATP-binding subunit.	ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.741
ACPL_4294	clpP-3	ACPL_4294	ACPL_1354	Uncharacterized protein; ATPases with chaperone activity, ATP-binding subunit.	ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.914
ACPL_4294	clpP-4	ACPL_4294	ACPL_7529	Uncharacterized protein; ATPases with chaperone activity, ATP-binding subunit.	ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.741
ACPL_4294	clpS	ACPL_4294	ACPL_1163	Uncharacterized protein; ATPases with chaperone activity, ATP-binding subunit.	ATP-dependent Clp protease adapter protein clpS; Belongs to the ClpS family.	0.703
ACPL_4294	dnaJ	ACPL_4294	ACPL_1406	Uncharacterized protein; ATPases with chaperone activity, ATP-binding subunit.	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.706
ACPL_4294	dnaJ-2	ACPL_4294	ACPL_202	Uncharacterized protein; ATPases with chaperone activity, ATP-binding subunit.	Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]	0.706
ACPL_4294	grpE	ACPL_4294	ACPL_201	Uncharacterized protein; ATPases with chaperone activity, ATP-binding subunit.	Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	0.685
ACPL_4783	ACPL_4294	ACPL_4783	ACPL_4294	Nephrocystin-3; FOG: TPR repeat.	Uncharacterized protein; ATPases with chaperone activity, ATP-binding subunit.	0.676
ACPL_4783	clpC-2	ACPL_4783	ACPL_6603	Nephrocystin-3; FOG: TPR repeat.	clpA-like ATP-dependent Clp protease; ATPases with chaperone activity, ATP-binding subunit.	0.676
ACPL_4783	grpE	ACPL_4783	ACPL_201	Nephrocystin-3; FOG: TPR repeat.	Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	0.765
clpC-2	ACPL_4294	ACPL_6603	ACPL_4294	clpA-like ATP-dependent Clp protease; ATPases with chaperone activity, ATP-binding subunit.	Uncharacterized protein; ATPases with chaperone activity, ATP-binding subunit.	0.703
clpC-2	ACPL_4783	ACPL_6603	ACPL_4783	clpA-like ATP-dependent Clp protease; ATPases with chaperone activity, ATP-binding subunit.	Nephrocystin-3; FOG: TPR repeat.	0.676
clpC-2	clpP	ACPL_6603	ACPL_1841	clpA-like ATP-dependent Clp protease; ATPases with chaperone activity, ATP-binding subunit.	Protease subunit of ATP-dependent Clp proteases; Belongs to the peptidase S14 family.	0.727
clpC-2	clpP-2	ACPL_6603	ACPL_1353	clpA-like ATP-dependent Clp protease; ATPases with chaperone activity, ATP-binding subunit.	ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.771
clpC-2	clpP-3	ACPL_6603	ACPL_1354	clpA-like ATP-dependent Clp protease; ATPases with chaperone activity, ATP-binding subunit.	ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.923
clpC-2	clpP-4	ACPL_6603	ACPL_7529	clpA-like ATP-dependent Clp protease; ATPases with chaperone activity, ATP-binding subunit.	ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.741
clpC-2	clpS	ACPL_6603	ACPL_1163	clpA-like ATP-dependent Clp protease; ATPases with chaperone activity, ATP-binding subunit.	ATP-dependent Clp protease adapter protein clpS; Belongs to the ClpS family.	0.737