STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_4297ABC-type multidrug transport system, permease component. (264 aa)    
Predicted Functional Partners:
ACPL_4296
Antibiotic transport system ATP-binding protein; ABC-type sugar transport systems, ATPase components.
 
    0.961
ACPL_4298
Two-component system, NarL family, sensor histidine kinase DesK; Signal transduction histidine kinase.
 
    0.869
ACPL_4299
yfiK-like uncharacterized transcriptional regulatory protein; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
     0.852
ACPL_3339
Two-component system, NarL family, sensor histidine kinase DesK; Signal transduction histidine kinase.
 
    0.551
ACPL_4295
Uncharacterized protein.
       0.548
ACPL_3750
Hypothetical protein; Nitroreductase.
 
    0.542
ACPL_3818
Two-component system, NarL family, response regulator DesR; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
     0.535
pdr1-4
Pleiotropic drug resistance protein 1; ABC-type multidrug transport system, permease component.
 
  
  0.478
ACPL_3192
Nitroreductase.
 
    0.469
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
     
 0.453
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.