STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xerDTyrosine recombinase xerC; Site-specific recombinase XerD; Belongs to the 'phage' integrase family. (310 aa)    
Predicted Functional Partners:
ACPL_4303
Ribose import ATP-binding protein rbsA; ATPase components of various ABC-type transport systems, contain duplicated ATPase.
       0.785
ftsK
DNA segregation ATPase FtsK/SpoIIIE and related proteins.
  
   
 0.672
ACPL_6333
ATPases involved in chromosome partitioning.
 
   
 0.618
parA
Formate-tetrahydrofolate ligase; ATPases involved in chromosome partitioning.
 
   
 0.597
uppP-2
Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
       0.535
ACPL_4302
Putative transcriptional regulator, GntR family; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.
       0.503
parB
Putative chromosome-partitioning protein parB; Predicted transcriptional regulators; Belongs to the ParB family.
  
  
 0.503
ACPL_4301
yyaP-like uncharacterized protein; Dihydrofolate reductase.
       0.479
trcF
Transcription-repair coupling factor (superfamily II helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
   
 0.409
apt
Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins.
  
    0.407
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.