Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_433Transcriptional regulator, ArsR family; Predicted transcriptional regulators. (189 aa)    
Predicted Functional Partners:
ACPL_434
Permeases of the major facilitator superfamily.
       0.616
ACPL_432
Helicase IV; Superfamily I DNA and RNA helicases.
 
     0.605
ACPL_431
Luciferase-like monooxygenase; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.
 
     0.587
mqnA
Periplasmic solute-binding protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
       0.570
ACPL_7308
Mini-circle uncharacterized 19.1 kDa protein.
  
     0.533
ACPL_1442
Hypothetical protein.
  
     0.413
ACPL_4205
Beta-galactoside-specific lectin 3.
  
     0.411
ACPL_8147
Uncharacterized protein conserved in bacteria.
  
     0.409
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (20%) [HD]