Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ACPL_4340HTH-type transcriptional repressor yvoA; Predicted transcriptional regulators. (118 aa)    
Predicted Functional Partners:
nadR
Transcriptional regulator nadR; FAD synthase.
   
    0.860
ACPL_4339
MFS transporter, UMF1 family; Permeases of the major facilitator superfamily.
       0.653
ACPL_1118
Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.
   
    0.535
ACPL_7632
Chromosome initiation inhibitor; Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
   
    0.520
fur
Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
   
    0.511
ACPL_4336
Hypothetical protein; Predicted GTPases (dynamin-related).
  
    0.485
ACPL_4338
Hypothetical protein.
       0.474
ACPL_4337
Hypothetical protein; Translation elongation factors (GTPases).
       0.465
ACPL_4341
Translation initiation factor IF-2; ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components.
       0.445
ACPL_5319
Membrane-bound protein lytR; Transcriptional regulator.
  
    0.434
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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