STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ohrOrganic hydroperoxide resistance protein-like 2; Predicted redox protein, regulator of disulfide bond formation. (139 aa)    
Predicted Functional Partners:
ohrR
Transcriptional regulators.
 
  
 0.871
ACPL_2699
DNA protection during starvation protein; DNA-binding ferritin-like protein (oxidative damage protectant); Belongs to the Dps family.
  
  
 0.654
ACPL_1571
Organic hydroperoxide resistance transcriptional regulator; Transcriptional regulators.
 
  
 0.563
katE
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
  
 0.528
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
      
 0.521
ACPL_5452
Prostaglandin reductase 1; Putative NADP-dependent oxidoreductases.
 
    0.491
ACPL_4355
yjdG-like uncharacterized N-acetyltransferase; Acetyltransferases, including N-acetylases of ribosomal proteins.
       0.483
ACPL_2549
CsbD family protein; Belongs to the UPF0337 (CsbD) family.
  
  
 0.465
ACPL_2807
Putative CsbD-like family protein; Belongs to the UPF0337 (CsbD) family.
  
  
 0.465
ACPL_4358
Alpha-1,2-mannosidase.
       0.435
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.