Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACPL_4377Hypothetical protein. (331 aa)    
Predicted Functional Partners:
ACPL_4378
Histidinol-phosphatase (PHP family); Histidinol phosphatase and related hydrolases of the PHP family; Belongs to the PHP hydrolase family. HisK subfamily.
       0.757
ACPL_2439
Phosphate import ATP-binding protein pstB; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
     
  0.549
ACPL_4376
Putative signaling protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
       0.542
ACPL_4375
Uncharacterized protein.
       0.519
drrB
Daunorubicin resistance transmembrane protein; ABC-type multidrug transport system, permease component.
 
 
  0.496
ACPL_3816
ABC-2 type transporter; ABC-type multidrug transport system, permease component.
 
 
  0.495
ACPL_6580
Putative pleiotropic drug resistance protein 7; ABC-type multidrug transport system, permease component.
 
 
  0.494
ACPL_882
Peptide/nickel transport system substrate-binding protein; ABC-type dipeptide transport system, periplasmic component.
     
  0.494
nodJ
Nodulation protein J; ABC-type multidrug transport system, permease component.
 
 
  0.491
ACPL_5451
Transcription elongation factor spt5; PPE-repeat proteins.
  
 
   0.485
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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