STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_439Hypothetical protein; Lactoylglutathione lyase and related lyases. (130 aa)    
Predicted Functional Partners:
tetR-9
Tetracycline repressor protein class E; Transcriptional regulator.
 
     0.870
ACPL_438
Non-specific serine/threonine protein kinase; Superfamily II DNA/RNA helicases, SNF2 family.
       0.689
nadR
Transcriptional regulator nadR; FAD synthase.
   
    0.644
ACPL_437
Hypothetical protein.
       0.524
ACPL_1894
Putative HTH-type transcriptional regulatory protein; Predicted transcriptional regulators.
  
    0.509
mqnC
Radical SAM domain-containing protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
       0.481
tetR-18
Tetracycline repressor protein class H; Transcriptional regulator.
 
     0.438
ACPL_6818
Fatty acid metabolism regulator protein; Transcriptional regulator.
 
    0.403
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.