STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tetR-9Tetracycline repressor protein class E; Transcriptional regulator. (253 aa)    
Predicted Functional Partners:
ACPL_439
Hypothetical protein; Lactoylglutathione lyase and related lyases.
 
     0.870
mqnC
Radical SAM domain-containing protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
       0.661
tetR-6
Tetracycline repressor protein class H; Transcriptional regulator.
  
     0.537
ACPL_438
Non-specific serine/threonine protein kinase; Superfamily II DNA/RNA helicases, SNF2 family.
       0.499
tetR-12
Tetracycline repressor protein class G; Transcriptional regulator.
  
     0.453
ACPL_5179
yndB-like uncharacterized protein.
  
     0.445
tetR-14
Tetracycline repressor protein class G; Transcriptional regulator.
  
     0.437
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.