Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_4427Transcriptional regulator, MarR family; Transcriptional regulators. (180 aa)    
Predicted Functional Partners:
ACPL_4426
Enterobactin exporter entS; Permeases of the major facilitator superfamily.
 
     0.852
efeU
Ferrous iron permease efeU; High-affinity Fe2+/Pb2+ permease.
       0.538
efeO
ycdO-like uncharacterized protein; Predicted periplasmic lipoprotein involved in iron transport.
       0.538
ACPL_4212
Aminoglycoside phosphotransferase.
  
     0.518
ACPL_6242
Hypothetical protein.
  
    0.497
ACPL_940
Hypothetical protein.
  
     0.486
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (14%) [HD]