Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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fdh-2Alcohol dehydrogenase GroES domain protein; Threonine dehydrogenase and related Zn-dependent dehydrogenases. (389 aa)    
Predicted Functional Partners:
ACPL_4455
Hypothetical protein.
  
    0.794
ACPL_1344
Putative 17.2 kDa protein in melC2-rnhH intergenic region; Predicted integral membrane protein.
 
    0.636
ACPL_2700
Hypothetical protein; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
  
 0.568
pepA
Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.
  
    0.552
ACPL_6169
Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
  
 0.551
ACPL_4453
Hypothetical protein; Hydrolases of the alpha/beta superfamily.
       0.444
ACPL_5250
tRNA (adenine-N1-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
     
  0.426
trmB
tRNA (guanine-N7-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
     
  0.426
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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