Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACPL_4461Hypothetical protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (227 aa)    
Predicted Functional Partners:
ACPL_4462
Phosphoglycerate mutase 1.
 
     0.932
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 0.900
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
  
 0.781
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
 0.781
pks2A
Polyketide synthase modules and related proteins.
  
 0.775
pks1B
Polyketide synthase modules and related proteins.
  
 0.769
pks3B
Polyketide synthase modules and related proteins.
  
 0.769
pks3C
Polyketide synthase modules and related proteins.
  
 0.755
ACPL_6195
Polyketide synthase modules and related proteins.
  
 0.680
ACPL_3917
Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.670
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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