STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_4471Transcriptional regulator, LuxR family; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (343 aa)    
Predicted Functional Partners:
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
   
 
 0.832
nuoG
NADH dehydrogenase I subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
   
 
 0.762
ACPL_2318
Signal transduction histidine kinase.
  
 
 0.744
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
   
 
 0.741
ACPL_2274
Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
 
 0.720
nuoE
NADH:ubiquinone oxidoreductase 24 kD subunit.
   
   0.708
ACPL_5341
NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit.
  
 
 0.682
ACPL_450
NADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
   
 
 0.677
ACPL_3560
Serine/threonine protein kinase; Predicted ATPase.
  
 
 0.647
ACPL_4809
Two-component system sensor protein; Signal transduction histidine kinase.
   
 
 0.643
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.