Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_4480Hypothetical protein; Histone acetyltransferase HPA2 and related acetyltransferases. (240 aa)    
Predicted Functional Partners:
pdc
Pyruvate dehydrogenase (cytochrome); Thiamine pyrophosphate-requiring enzymes; Belongs to the TPP enzyme family.
  
  
 0.652
ACPL_7601
Hypothetical protein.
   
    0.615
mshD
Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
   
    0.612
citA
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.599
ACPL_2558
Citrate synthase.
  
 
 0.599
ACPL_5308
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.599
ACPL_549
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.599
ACPL_4481
Putative N-acetyltransferase; Histone acetyltransferase HPA2 and related acetyltransferases.
       0.555
ACPL_5158
Malate synthase; Belongs to the malate synthase family.
   
 
 0.549
ACPL_6612
Malate synthase.
   
 
 0.549
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (18%) [HD]