Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ank2Ankyrin-2; FOG: Ankyrin repeat. (515 aa)    
Predicted Functional Partners:
ACPL_4492
Hypothetical protein.
 
     0.950
ACPL_3980
Putative WD repeat-containing protein; FOG: WD40 repeat.
 
 
 0.863
dnaK-3
Molecular chaperone.
  
 0.848
ACPL_8364
Putative WD repeat-containing protein; FOG: WD40 repeat.
   
 0.844
ACPL_4493
Uncharacterized protein; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
   
   0.794
pks2A
Polyketide synthase modules and related proteins.
 
 0.781
ACPL_5037
Uncharacterized protein conserved in bacteria.
 
     0.769
ACPL_5038
ATPase associated with various cellular activities AAA_3; MoxR-like ATPases.
 
    0.759
ACPL_8205
Hypothetical protein.
  
 0.753
rpsC
Small subunit ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
    
 0.726
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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