Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACPL_4512RTX toxins and related Ca2+-binding proteins. (629 aa)    
Predicted Functional Partners:
ACPL_4511
Hypothetical protein.
       0.782
ACPL_4510
Hypothetical protein.
       0.781
ACPL_4988
Hypothetical protein.
  
     0.627
ACPL_3699
Sensor protein kinase walK; Signal transduction histidine kinase.
  
 
   0.621
phy
Putative histidine kinase, classic; Osmosensitive K+ channel histidine kinase.
  
 
   0.614
ACPL_7919
Flagellar protein FliO/FliZ.
 
     0.602
ACPL_2012
Putative histidine kinase, classic; Signal transduction histidine kinase.
  
 
   0.593
pclO-2
Protein piccolo; Type V secretory pathway, adhesin AidA.
 
 
   0.558
phy1-6
Putative histidine kinase, classic; Osmosensitive K+ channel histidine kinase.
  
 
   0.545
ACPL_6911
Collagen alpha-4(VI) chain; Secreted and surface protein containing fasciclin-like repeats.
  
 0.517
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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