STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_4599Uncharacterized protein conserved in bacteria. (163 aa)    
Predicted Functional Partners:
nadR
Transcriptional regulator nadR; FAD synthase.
   
    0.644
ACPL_6810
Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.
 
    0.585
ACPL_4690
HTH-type transcriptional activator rhaS; Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain.
 
    0.579
nadE-2
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
       0.576
ACPL_4597
Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding.
       0.568
ACPL_6326
Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.
  
    0.500
ACPL_5319
Membrane-bound protein lytR; Transcriptional regulator.
   
    0.445
ACPL_8294
Membrane-bound protein lytR; Transcriptional regulator.
   
    0.445
ACPL_4673
NAD-dependent protein deacetylases, SIR2 family.
  
    0.420
cobB-3
NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.
  
    0.420
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.