Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
arsR-2Arsenical resistance operon repressor; Predicted transcriptional regulators. (119 aa)    
Predicted Functional Partners:
ACPL_4600
Activator of HSP90 ATPase 1 family protein.
 
    0.867
ACPL_2290
Transcriptional repressor sdpR; Predicted transcriptional regulators.
  
     0.773
ACPL_4602
Hypothetical protein.
       0.737
ACPL_5200
Transcriptional repressor sdpR; Predicted transcriptional regulators.
  
     0.722
ACPL_1334
Predicted transcriptional regulators.
  
     0.686
ACPL_5257
Hypothetical protein.
 
    0.596
ACPL_2789
Transcriptional regulator, ArsR family; Predicted transcriptional regulators.
  
     0.552
ACPL_4603
Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family.
       0.501
ACPL_4604
yjiR-like uncharacterized HTH-type transcriptional regulator; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.
       0.488
ACPL_5199
Activator of HSP90 ATPase 1 family protein.
 
  
 0.406
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.