Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_4611Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (277 aa)    
Predicted Functional Partners:
sucA
2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
   
 0.686
polA-2
DNA polymerase I; 5'-3' exonuclease (including N-terminal domain of PolI).
  
    0.635
ACPL_1533
2-oxoisovalerate dehydrogenase E1 component; Transketolase.
   
 0.545
ACPL_3124
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
   
 0.545
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.532
ACPL_4609
3-oxoacyl-[acyl-carrier-protein] reductase; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.480
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.439
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.439
ACPL_4612
C-type lectin domain family 4 member G; Chromosome segregation ATPases.
       0.438
pks2A
Polyketide synthase modules and related proteins.
  
 0.432
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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