Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_4643Soluble pyridine nucleotide transhydrogenase; Thioredoxin reductase. (511 aa)    
Predicted Functional Partners:
ACPL_4642
Monocarboxylate transporter 2; Permeases of the major facilitator superfamily.
 
     0.925
arsC
Protein-tyrosine phosphatase, low molecular weight; Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
 
   
 0.591
ACPL_2119
Hypothetical protein.
 
 
 0.570
ACPL_4644
Cadmium efflux system accessory protein; Predicted transcriptional regulators.
 
   
 0.565
ACPL_7413
ybbN-like uncharacterized protein; Thioredoxin domain-containing protein.
  
 
 0.504
trxA
Thioredoxin-1; Thiol-disulfide isomerase and thioredoxins.
  
 
 0.504
ACPL_8372
Thioredoxin-1; Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
  
 
 0.504
dsbF
Thiol-disulfide oxidoreductase resA; Thiol-disulfide isomerase and thioredoxins.
 
 
 
 0.480
paaK
Phenylacetic acid degradation NADH oxidoreductase; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
   
 
 0.464
ACPL_5396
Oxidoreductase FAD-binding domain protein; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
   
 
 0.464
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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