STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_4662Glycerol-3-phosphate regulon repressor; Transcriptional regulators of sugar metabolism. (252 aa)    
Predicted Functional Partners:
ACPL_6373
Phosphofructokinase; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.
 
  
 0.794
ACPL_1513
PfkB domain protein; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB).
 
  
 0.683
ACPL_4663
GDP-mannose pyrophosphatase nudK; NTP pyrophosphohydrolases including oxidative damage repair enzymes.
 
     0.645
ACPL_7140
CoA-binding domain protein; Acyl-CoA synthetase (NDP forming).
    
   0.483
ACPL_4664
Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
       0.455
ACPL_4661
Transcriptional regulators.
     
 0.435
ACPL_6645
Sodium/glucose cotransporter 1; Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    0.419
iolB
5-deoxy-glucuronate isomerase; Uncharacterized enzyme involved in inositol metabolism.
  
  
 0.411
rhaD
Rhamnulose-1-phosphate aldolase/alcohol dehydrogenase.
  
  
 0.410
ACPL_2746
Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
 
    0.400
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.