Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tetR-11Tetracycline repressor protein class H; Transcriptional regulator. (230 aa)    
Predicted Functional Partners:
lys1
Saccharopine dehydrogenase and related proteins.
 
     0.612
ACPL_5588
Hypothetical protein.
  
     0.612
ACPL_5000
Hypothetical protein.
 
   
 0.584
ACPL_5944
Putative mobilization relaxase component.
  
     0.575
ACPL_5942
Hypothetical protein.
  
     0.574
ribA-2
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
      
 0.562
ACPL_5932
Hypothetical protein.
  
     0.558
ACPL_2383
Hypothetical protein; Predicted enzyme of the cupin superfamily.
  
     0.557
xthA
Exonuclease III.
  
    0.549
ACPL_6791
Endonuclease/exonuclease/phosphatase; Exonuclease III.
  
    0.549
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.