close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_4703Signal transduction histidine kinase. (337 aa)    
Predicted Functional Partners:
resD
Transcriptional regulatory protein yycF; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
   0.959
ACPL_4707
3-demethylubiquinone-9 3-methyltransferase; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4- benzoquinol methylase.
 
     0.878
ACPL_4709
Glycosyltransferases involved in cell wall biogenesis.
 
     0.871
ACPL_4708
Uncharacterized protein conserved in bacteria.
 
     0.867
ACPL_4706
Hypothetical protein; Sulfite oxidase and related enzymes.
 
     0.847
ACPL_4705
Hypothetical protein.
       0.816
ACPL_2319
Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
   0.804
ompR
Transcriptional regulatory protein yycF; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
   0.782
ACPL_580
Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
   0.751
phoB
Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
   0.746
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: medium (56%) [HD]