Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_4710UDP-glucose 4-epimerase; Nucleoside-diphosphate-sugar epimerases. (339 aa)    
Predicted Functional Partners:
ACPL_4711
Hypothetical protein.
 
   
 0.966
ACPL_4709
Glycosyltransferases involved in cell wall biogenesis.
 
  
 0.952
ACPL_4708
Uncharacterized protein conserved in bacteria.
 
   
 0.948
rmlD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
  
 0.939
ACPL_3183
dTDP-4-dehydrorhamnose reductase.
  
 0.939
ACPL_4291
dTDP-4-dehydrorhamnose reductase.
  
 0.939
ACPL_4706
Hypothetical protein; Sulfite oxidase and related enzymes.
 
     0.922
ACPL_4707
3-demethylubiquinone-9 3-methyltransferase; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4- benzoquinol methylase.
 
     0.920
rmlB
dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
 
0.884
acbB
dTDP-glucose 4,6-dehydratase; Probably involved in the biosynthesis of the acarviose moiety of the alpha-glucosidase inhibitor acarbose. Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D- xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction (By similarity). Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
 
0.884
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.