Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_4727Signal transduction histidine kinase. (497 aa)    
Predicted Functional Partners:
cheR
Methylase of chemotaxis methyl-accepting proteins.
   
 0.928
ACPL_2274
Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 
 0.861
ACPL_2318
Signal transduction histidine kinase.
 
 
0.836
ACPL_2013
Sensor histidine kinase and response regulator of a two component complex; Signal transduction histidine kinase.
 
 0.834
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
 
 
0.832
ACPL_3427
Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Osmosensitive K+ channel histidine kinase.
 
 
0.827
phoR
Sensory box histidine kinase PhoR; Signal transduction histidine kinase.
 
 
0.826
ACPL_4649
Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.
 
0.818
ACPL_699
Chemotaxis response regulator protein-glutamate methylesterase of group 3 operon; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 
    0.814
ACPL_701
Putative transcriptional regulator ycf27; FOG: CheY-like receiver.
    0.811
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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